Ipamorelin (10mg)

All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months.
Once the peptides are reconstituted (mixed with bacteriostatic water), they must be stored in the fridge to maintain stability. After reconstitution, the peptides will remain stable for up to 30 days.

Lyophilization is a unique dehydration process, also known as cryodesiccation, where the peptides are frozen and then subjected to low pressure. This causes the water in the peptide vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure known as lyophilized peptide. The puffy white powder can be stored at room temperature until you're ready to reconstitute it with bacteriostatic water.

Once peptides have been received, it is imperative that they are kept cold and away from light. If the peptides will be used immediately, or in the next several days, weeks or months, short-term refrigeration under 4C (39F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically

• Ipamorelin and Alleviation of Negative Corticosteroid Effects

Glucocorticoids,
frequently employed in treating inflammatory conditions spanning cancer
to autoimmune diseases, exhibit considerable side effects, curbing
their clinical utility. Addressing these side effects holds potential
for enhancing medication dosages and prolonging treatment, positively
impacting morbidity and mortality rates. Ipamorelin, evident in various
studies, has demonstrated the capacity to mitigate or reverse the
adverse effects induced by glucocorticoid use.

• Ipamorelin and Skeletal Health

Long-term
glucocorticoid usage is associated with a significant challenge—loss of
bone density leading to an elevated risk of fractures. While current
therapies pose side effects, limited efficacy, or high costs, Ipamorelin
offers a cost-effective alternative with minimal side effects. Rat
studies indicate Ipamorelin's ability to halt corticosteroid-induced
bone loss, fostering a four-fold increase in bone formation.
Additionally, Ipamorelin enhances systemic bone mineral density,
fortifying both existing and newly formed bone, while mitigating muscle
wasting and visceral fat deposition associated with steroid use.

• Ipamorelin and its Impact on Muscle Growth

Evidence
suggests that Ipamorelin, as a growth hormone secretagogue, may
counteract the catabolic effects of glucocorticoids on muscle. Research
involving rats administered glucocorticoids reveals a reduction in liver
nitrogen wasting and improved nitrogen balance following Ipamorelin
administration. Combating muscle catabolism and bone density loss with a
single drug presents significant potential for patients requiring
glucocorticoid therapy.

• Ipamorelin and Diabetes

Studies
in diabetic rats indicate that Ipamorelin augments insulin release,
possibly through indirect stimulation of calcium channels in pancreatic
islet cells. This effect sheds light on Ipamorelin's potential in
understanding the functional constraints of type 2 diabetes and its role
in developing novel therapeutic or preventive measures.

• Investigation of Ipamorelin for Post-Operative Ileus Treatment

Post-operative
ileus (POI), prevalent after certain surgeries, significantly impacts
patients' recovery by delaying oral nutrition intake. Ipamorelin's
exploration in clinical trials aimed at reducing POI duration indicates a
potential to expedite the time to the first meal by approximately 12
hours. While early trials faced limitations, ongoing research and
exploration of combination therapies, incorporating Ipamorelin, could
enhance effectiveness.

• Ipamorelin as a Ghrelin Receptor Probe

As
a selective ghrelin receptor agonist with robust binding, Ipamorelin
holds promise for application as a probe in positron emission tomography
(PET) for aiding in cancer diagnosis and heart failure. In vitro
studies confirm Ipamorelin's feasibility for PET, emphasizing its
potential utility in vivo, necessitating further testing and
standardization of interpreting PET studies.

In
conclusion, Ipamorelin, despite its current status as a neglected drug
in research, offers multifaceted therapeutic potential and serves as a
valuable tool for comprehending various disease states and their
physiological impacts. Future research initiatives may reignite interest
in Ipamorelin, unraveling its unique peptide benefits.